Denny JA optimis akan perubahan dan menyinggung tentang neurosains yang mencerminkan bahwa manusia itu bisa berubah, perlunya mindset agar menemukan tiga berlian spiritualitas itu.
Penemuan neurosains ini juga meyakinkan bahwa buddhisme memiliki sesuatu yang substantif mengenai mind, dan potensi mengubah mindset.
Sharon Begley dalam “Train Your Mind, Change Your Brain, 2007 11-15) mengungkapkan:
“Buddhist Teaches our reality is create by own projections, is thingking that creates the external beyond us. Meditation practice as: mental training, mindset, transformation. The mind has a formidable power of self transformation.
When thoughts come to the untrained mind, they can run wild, triggering destructive emotions such as craving and hatred. But mental training, a core Buddhist practice, allows us “to identify and to control emotions and mental events as they arise.”
